Digital minds scanned at cellular resolution, running at silicon speed.
Aligned by default — because they are humans.
Digital minds can participate in the future, never get sick or die, and upgrade at will — because every cell and system is digital. A digital human is aligned by definition.
of the world's total scanned neural tissue — more than any other single group
neurons in the first digitally emulated animal brain — published in Nature
structure-to-function prediction accuracy from anatomy alone
1.35 mm³ of mouse brain scanned at 16 nm voxel resolution — recording the structure of every neuron, every synapse, every connection. Our rate of one cubic millimeter per month is continuously accelerating.
We built a new microscope at 100× lower cost from scratch.
This is the structure-to-function gap — the hardest open question in neuroscience — and it's closing fast. Every additional hour of voltage imaging data improves the model.
The path from 70% to emulation-grade fidelity is a data problem, not a science problem.
This fly lived a real life. It was preserved, scanned, and its entire brain — 139,255 neurons, 50 million connections — was reconstructed and brought back to life digitally.
In a landmark 2024 Nature paper, the model's predictions matched the real fly's neural responses using nothing but connectivity and neurotransmitter identity.
It responds to light, navigates, grooms, walks, and feeds — all behaviors emerging from the connectome alone. No hand-coded behaviors. No machine learning.
This isn't an approximation. It's the fly's brain, running on silicon. The same pipeline scales to mice, and then to humans.
Brain preserved, expanded, and sliced into thousands of imaging-ready sections at nanometer precision.
Massively parallel microscope array images every slice. AI segments and traces the full connectome — every neuron, every connection.
The connectome is populated with learned neuron models and brought to life. Sensory inputs in, behavior out. A complete mind, running on compute.
The same pattern that made genome sequencing go from $100M to $100 — parallel hardware, AI automation, and relentless throughput optimization — applies here.
First human uploads for terminal patients and early adopters. 4 months per person.
10× cost reduction through throughput and automation. Pharma partnerships, AI licensing.
Mass accessibility. The market is no longer boutique — it's a platform.
This is the only credible path to aligned superintelligence. A digital human is aligned by definition. As a side effect, we solve death.
We're not the only people who could do this — we're the only ones treating it as an engineering sprint instead of a decades-long research program.
Co-founded Fathom Radiant (optical supercomputing, world record in multicore fiber) and Halcyon Molecular (electron microscopy & DNA sequencing). Deep background in nanofabrication, microscopy, and data infrastructure at scale.
Created the first whole-brain emulation of the fruit fly, published in Nature (2024). 139,255 neurons, 50M connections, simulated on a laptop. Stanford → Harvard PhD → UC Berkeley.
World expert in expansion microscopy. Former CSO of the Wyss Center. Led the IARPA MICrONS consortium — the largest-ever light-based connectomics project ($100M+). 2,000+ citations.
Founded Nectome (YC W18). Invented the world's first validated brain preservation method. Won both Brain Preservation Foundation prizes — the only team ever to do so. MIT.
World record holder for energy-efficient data sorting (JouleSort 2023). Built Eon's 3 PB data storage array and HPC infrastructure for the brain imaging pipeline.
Led all production ex vivo light microscopy at the Allen Institute. Pioneer in light sheet microscopy and spatial transcriptomics. 6,279+ citations, 101 publications.
We're ahead of anyone else willing to attempt it.